0.60
CiteScore
0.186
SJR
0.447
SNIP
 
 

A Concise Review on Analytical Profile of Valsartan

Atul A. Shirkhedkar 1  ,  
Amod S. Patil 3,  
 
1
Department of Pharmaceutical Chemistry, Department of Pharmaceutical Chemistry R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur Dist: Dhule(MS) India 425 405
2
Department of Pharmaceutical Chemistry, R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dist. Dhule (MS) India 424 405
3
Department of Pharmaceutical Chemistry R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur Dist: Dhule (MS) India 425 405
4
Principal R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur Dist: Dhule (MS) India 425 405
Eurasian J Anal Chem 2017;12(4)
Publish date: 2017-01-04
KEYWORDS:
TOPICS:
ABSTRACT:
Valsartan (VAL) is an orally active angiotensin-II receptor type-I antagonist. VAL is available alone in dosage form as well as multicomponent formulation with various antihypertensive drugs like nifedipine, hydrochlorothiazide, ramipril, amlodipine and nebivolol hydrochloride, for the management of hypertension. The present investigation assesses the various approaches for analysis of VAL in bulk drug as well as formulated products. A concise review represents the compilation and discussion of about more than 90 analytical methods which includes HPLC, HPTLC, capillary electrophoresis, electrochemical methods and UV-Spectrophotometry methods implemented for investigation of VAL in biological matrices, bulk samples and in different dosage formulations. The review describes the percentage utilization of the various approaches for analysis of VAL. The statistical data regarding the utility of these methods for estimation of VAL published during 2001 to 2016 have been included.
CORRESPONDING AUTHOR:
Atul A. Shirkhedkar   
Department of Pharmaceutical Chemistry, Department of Pharmaceutical Chemistry R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur Dist: Dhule(MS) India 425 405, Karwand Naka, 425405 Shirpur Dist: Dhule(MS), India
eISSN:1306-3057