0.60
CiteScore
0.186
SJR
0.447
SNIP
 
 

Design of Experiments based validated HPTLC method for quantification of Oxybenzone and Avobenzone in Personal care products

kavitha j 1  ,  
 
1
SRM College of Pharmacy
2
SRM COLLEGE OF PHARMACY
Eurasian J Anal Chem 2017;12(4)
Publish date: 2017-01-04
KEYWORDS:
TOPICS:
ABSTRACT:
Background:
A rapid, simple and economic High Performance Thin Layer Chromatography (HPTLC) method for the simultaneous quantification of Oxybenzone and Avobenzone in various personal care products available in local markets in and around Chennai is developed and validated. Central Composite statistical design (CCD) with three factors and one response was employed to study the robustness of the developed method.

Material and methods:
Introduction Method validation Robustness study using CCD

Results:
The developed and optimized method was validated. The content of Oxybenzone and Avobenzone in various personal care products were quantified

Conclusions:
The developed method was found to be simple, novel, sensitive, precise, accurate and robust for simultaneous estimation of Oxybenzone and Avobenzone in personal care products.

CORRESPONDING AUTHOR:
kavitha j   
SRM College of Pharmacy, chandrasekaran salai, 600082 chennai, India
eISSN:1306-3057