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Magnetic and Spectroscopic Methods for Structural Characterization of Paramagnetic Hematoporphyrin IX Complex With Cu(II)
| 1 | University of Sofia, Faculty of Chemistry, 1, J. Bourchier Bulv., 1164 Sofia, Bulgaria |
CORRESPONDING AUTHOR
Galina G. Gencheva
Department of Analytical Chemistry, Faculty of Chemistry, “St. Kliment Ohridsky” University of Sofia, 1 J. Bourchier Boulevard, 1164 Sofia, Bulgaria
Department of Analytical Chemistry, Faculty of Chemistry, “St. Kliment Ohridsky” University of Sofia, 1 J. Bourchier Boulevard, 1164 Sofia, Bulgaria
Online publication date: 2007-10-01
Publication date: 2007-10-01
Eurasian J Anal Chem 2008;3(1):79–90
KEYWORDS
ABSTRACT
A paramagnetic metaloporphyrin type complex [Cu(II)(Hp-2H)].2H2O has been obtained during the reaction of Cu(II) and hematoporphyrin IX ((7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H-23H-porphyn-2,18-dipropionic acid) - Hp, I) in alkaline aqueous medium. The solution and solid state structure of the complex were studied through UV-Vis, IR and EPR spectroscopic methods. The applied simulation procedure using the parameters from the experimental EPR spectrum proved the square planar structure of the complex with symmetrical coordination of the porphyrin ligand to Cu(II) via the four pyrrole N-atoms in the porphyrin macrocycle.
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