Micellar Studies of Local Anticonvulsant Gabapentin in Aqueous Electrolyte Solution
 
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Department of Chemistry, Punjabi University, Patiala-147002, India
CORRESPONDING AUTHOR
Ashok Kumar Malik   

Department of Chemistry, Punjabi University, Patiala-147002, India
Online publish date: 2007-06-15
Publish date: 2007-06-15
 
Eurasian J Anal Chem 2007;2(2):93–100
KEYWORDS
ABSTRACT
Specific conductivity of aqueous electrolyte solution of anticonvulsant gabapentin (2-[1-(aminomethyl)cyclohexyl]ethanoicacid) has been determined in the temperature range of 303-338 K. The critical micelle concentrations (cmc), ionization degree (α) and the counterion binding of the micelle (β), were estimated from the dependence of specific conductivity on concentration. Thermodynamic parameters, such as standard Gibbs free energy (ΔG°), enthalpy (ΔH°) and entropy (ΔS°) of micellization, were estimated by the mass action model.
 
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