Synthesis, Separation and Determination of Metal Dithiocarbamates Complexes by HPLC-ICP-MS
Subhash Bajia 1
,  
 
 
More details
Hide details
1
Department of Pure and Applied Chemistry, Maharshi Dayanand Saraswati University, Ajmer 305 009, India
CORRESPONDING AUTHOR
Krishan G. Ojha   

Department of Pure and Applied Chemistry, Maharshi Dayanand Saraswati University, Ajmer 305 009, India
Publish date: 2017-11-02
 
Eurasian J Anal Chem 2013;8(3):107–111
KEYWORDS
ABSTRACT
A rapid, simple and reliable spectroscopic technique has been developed for the determination of metal cations using dithiocarbamates moiety as chelating agent by HPLC. The method is based on the formation of stable colored dithiocarbamate complexes by reaction metal salt and dithiocarbamate moiety, which is then extracted methanol and separated with acetonitrile water mobile phase. The different analytical parameters affecting the method such as pH for extraction, solvent for extraction, mobile phase and type of the column. After the column elution the sample was allow to passes in to UV detector and then into ICP-MS. The separate data have been observed from UV detector and ICPMS for each sample and then from the help of both results the identification and determination of these complexes have been done. Satisfactory recovery from the spiked samples of standard metal ion suggests no interference of any excipients. The developed method was compared with other spectroscopic methods, no significant difference was observed
 
REFERENCES (15)
1.
Coffey TA, Foster GD. Hogarth G (1996) Molybdenum(VI) imidodisulfur complexes formed via double sulfur–carbon bond cleavage of dithiocarbamates. J. Chem. Soc. Dalton Trans, 2: 183-193.
 
2.
Law NA, Dietzsch W, Duffy NV (2003) A multinuclear (1H, 13C, 15N) NMR study of cis-halonitrosylbis(dithiocarbamato)iron(II) complexes: effect of replacement of S by Se. Polyhedron, 22, 3423-3432.
 
3.
Arain MA, Khuhawar MY, Bhanger MI (2002) Gas and liquid chromatography of metal chelates of pentamethylene dithiocarbamate. J. Chromatogr. 973: 235-241.
 
4.
Bond AM, Knight RW, Reust JB, Tucker DJ, Wallace GG (1986) Determination of metals in urine by direct injection of sample, high-performanc liquid chromatography and electrochemical or spectrophotometric detection. Analytica Chim. Acta, 182: 47.
 
5.
Jyothi Y, Sreedhar NY (2005) Extraction-stripping voltammetric determination of copper, cobalt and nickel in human serum. Bulletin of Electrochemistry, 21(5), 209-212.
 
6.
Magnusson LGB, Westerlund S, Zhang K (1982) Trace metal determinations in estuarine waters by electrothermal atomic absorption spectrometry after extraction of dithiocarbamate complexes into freon. Analytica chim. Acta, 144: 83-188.
 
7.
Daud JM, Alakili IM (2001) High Performance Liquid Chromatography Separations Of Metal-Pyrrolidine Dithiocarbamate Complexes. Malaysian Journal of Analytical Sciences 7(1): 113-120.
 
8.
K. W. Weissmahr, C. L. Houghton, D. L. Sedlak, Anal. Chem., 70 (22), 1998, 4800.
 
9.
Petsch M, Seipelt J, Mayer-Helm BX (2004) A novel pre-column derivatization reaction for the determination of dithiocarbamates in plasma by high-performance liquid chromatography Analytica Chimica Acta, 516 (1-2): 119-124.
 
10.
Arain MA, Khuhawar MY, Bhanger MI (2002) Gas and liquid chromatography of metal chelates of pentamethylene dithiocarbamate. Journal of Chromatography A, 973(1-2), 235.
 
11.
Wilnewski S, Beerand H, Wenclawiak BW (2006) HPLC, Extraction and Solubilities of Pd (II) and Rh (III)-Dialkyldithiocarbamates and Other Chelate Chemistry, Springer Berlin Heidelberg, 229.
 
12.
Shah NK, Wai CM (1989) Preconcentration of metal dithiocarbamate complexes on C18-bonded silica gel for neutron activation analysis. J Radio and Nucl Chem, 130(2): 451-459.
 
13.
Huchicki A (1967) Complexation reactions of dithiocarbamates, Talanta, 14: 1371-1392.
 
14.
Siddiqi KS, Nami SAA, Lutfullah, Chebude Y (2006) Template Synthesis of Symmetrical Transition Metal Dithiocarbamates. J Braz Chem Soc 17(1): 107-112.
 
15.
Siddiqi KS, Nami SAA, Chebude LY (2005) Synthesis, Characterization and Thermal Studies of Bipyridine Metal Complexes Containing Different Substituted Dithiocarbamates. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chem 35 (6): 445-451.
 
eISSN:1306-3057