Thiosemicarbazide derivatives (A1-A2) were synthesized by the reaction of (pbromo aniline and p-amino acetophenone ) respectively withcarbondisulfide (CS2) / hydrazine hydrate .Compounds (A1-A2) were allowed to react with aromatic benzaldehyde (p-N,N-dimethyl amino , p-chloro and p-hydroxybenzaldehyde) to form compounds of thiosemicarbazone (A3-A8) using fusion method.Quinazoline compounds (A9-A14) were also formed by reaction of (A3-A8) with anthranilic acid using fusion method . Compounds (A3- A8) were also reacted with maleic anhydride to form 1,3- oxazepine compounds (A15-A20) by fusion method. The prepaered compounds were identified by ( I.R ,1H.NMR, 13C.NMR and melting points. ) .