THE EFFECTIVENESS OF ANTIBIOTIC USE AGAINST COMMUNITY-ACQUIRED PNEUMONIA IN A TERTIARY HOSPITAL IN SOUTHERN VIETNAM
 
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Pham Ngoc Thach University of Medicine
Online publication date: 2018-05-18
Publication date: 2018-05-18
 
Eurasian J Anal Chem 2018;13(3):emEJAC04041
 
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ABSTRACT
Objectives: Community-acquired pneumonia affects millions of people every year all over the world, and the antibiotic resistance rate has continued to rise over the last few decades. Therefore, a study on the effectiveness of antibiotic use against community-acquired pneumonia is currently essential. We thus conducted such a study at TrungVuong General Hospital in Ho Chi Minh City, Vietnam, from August 2017 to March 2018. Methods: A descriptive cross-sectional study was conducted. The data was analysed using Microsoft Excel 2010, Minitab 16.0. We used Chi-squared (χ2) and Fisher’s exact tests to compare two resistance rates. The difference was considered to be statistically significant if p < 0.05. Results: Of the cases studied, 78.6% responded well to the first antibiotic treatment; 19.8% responded well to the second antibiotic treatment; and 1.3% responded well to the third antibiotic treatment. There remained 0.3%, meaning two patients, whose conditions were not improved, and they were moved to the ICU to be continuously observed and treated. Conclusion: The antibiotic combinations, including fluoroquinolone and mainly β-lactam, were effective as treatment after 72 hours in over 65% of the cases. There are only two combinations of macrolide and β-lactam that have been effective in 100% of cases as the first treatment for community-acquired pneumonia: ceftriaxone + azithromycin and ceftriaxone + azithromycin + vancomycin.
eISSN:1306-3057