Centella asiatica: Unveiling Its Role in Wound Healing and Tissue Regeneration
DOI:
https://doi.org/10.53555/ejac.v19i1.1126Keywords:
Wound, Morpholgy, Pharmacology action, Wound healing, Anti fungal ctivity, Anti inflammatory activity .Abstract
Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The efficacy of Centella asiatica for incision and burn wounds are not fully understood. Here, we report the wound healing activities of sequential hexane, ethyl acetate, methanol, and water extracts of Centella asiatica in incision and partial-thickness burn wound healing. There is a higher demand for nutrients which needs to be met. This is to reduce the risk of delay in wound healing which could lead to chronic wound. This is a systematic review of the effect of Centella asiatica on wound healing. Centella asiatica is a reputed medicinal plant used in the treatment of various skin diseases in the Indian system of medicine. The aerial parts and roots are used for medicinal purpose, and its chemical constituents have wide therapeutic applications in areas of antimicrobial, anti-inflammatory, anticancer, neuroprotective, antioxidant, and wound healing activities. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. it is widely distributed throughout tropical and subtropical regions of World. The use of Centella in food and beverages has increased over the years basically due to its beneficial functional properties. The therapeutic substances in C. asiatica are saponin-containing triterpene acids and their sugar esters, of which asiatic acid, madecassic acid and asiaticosides are considered to be the most important.
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