Assessment Of Essential Trace Elements, Acute Phase Reactants, And Biochemical Parameters In Stone Mine Workers And Healthy Controls In Western Rajasthan

Authors

  • Dr. Mahadev Choudhary
  • P Satynarayana
  • Prakash S Hundekar
  • Dr. Heethendra Kumar
  • Purohit Sunahara Dagur

DOI:

https://doi.org/10.53555/ejac.v19i1.1134

Abstract

Introduction: Silicosis is a serious lung disease caused by long-term exposure to crystalline silica dust in the workplace. The risk and development of silicosis are significantly influenced by the mineral composition of work environments.

Aim: The aim of this study is to evaluate the connection between mineral content in industrial environments and the likelihood of developing silicosis.

Methodology: This is a comparative cross-sectional study designed to assess the levels of essential trace elements, acute phase reactants, and biochemical parameters in stone mine workers and healthy controls in the western Rajasthan region.

Result: Pearson correlation indicated a significant relationship between increased occupational exposure and higher levels of copper, CRP, and ferritin, while lower zinc and vitamin D levels were also correlated with increased exposure.

In conclusion, The study revealed significant differences in essential trace elements, acute phase reactants, and vitamin levels between stone mine workers and healthy controls. The findings underscore the need for targeted health interventions to address nutritional deficiencies and monitor inflammatory markers among mine workers to mitigate health risks associated with occupational exposure.

Author Biographies

  • Dr. Mahadev Choudhary

    PhD Scholar, Pacific Institute of Medical Sciences, Sai Tirupati University, Udaipur, Rajasthan

  • P Satynarayana

    Professor guide, Pacific Institute of Medical Sciences, Sai Tirupati University, Udaipur, Rajasthan

  • Prakash S Hundekar

    Government Medical College, Barmer, Rajasthan

  • Dr. Heethendra Kumar

    Principal & Controller, Government Medical College Barmer, Rajasthan

  • Purohit Sunahara Dagur

    PhD Scholar, Pacific Institute of Medical Sciences, Sai Tirupati University, Udaipur, Rajasthan

References

NIOSH. Health Effects of Occupational Exposure to Respirable Crystalline Silica. U.S. Department of Health and Human Services. 2020.

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Moitra, S., et al. "Trace Elements in Respiratory Health: The Role of Zinc and Copper in Occupational Lung Disease." International Journal of Occupational Medicine, vol. 59, no. 4, 2022, pp. 415-420.

Das, B., et al. "Vitamin D Deficiency in Occupational Lung Disease: Implications for Prevention and Treatment." Journal of Occupational and Environmental Medicine, vol. 45, no. 5, 2021, pp. 199-205.

Li, J., et al. “Elevated Copper Levels in Industrial Workers: A Marker of Occupational Health Risk.” Toxicology and Applied Pharmacology, vol. 356, 2021, pp. 98-104.

Brown, J. R., et al. "Ferritin as a Biomarker for Silicosis and Other Occupational Lung Diseases." Journal of Inflammation Research, vol. 8, 2020, pp. 105-112

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Published

12-12-2024

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